Antifungal Activity of Some Benzimidazole-Hydrazones

Antifungal activity of selected benzimidazole compounds.

The comparative antifungal activity of four benzimidazole compounds was determined against 11 fungi.

Fungicidal activity of some o-nitrophenyl-hydrazones.

The antimycotic activity of 16 o-nitrophenylhydrazones against strains of Hansenula anomala, Saccharomyces cerevisiae, Candida parapsylosis, and Cryptococcus albidus was tested. All 16 compounds inhibited growth of the yeast strains. The inhibitory activity of the 4 methyl-derivatives substituted on the aromatic nucleus was particularly significant.

Study of Some Benzimidazole Compounds as Antibacterial and Antifungal Agents

There is a clinical need for new treatment option as a result of continued increase in the expression of resistance among bacterial and fungal pathogens. A number of compounds currently in development show promise. However, in some cases, there is concern that resistance may develop quickly to new compounds that are based on existing antimicrobial agents. So it is therefore desirable to develop...

synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives

Synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives

In recent years, the use of antifungal drugs in human medicine has increased, especially with the advent of AIDS epidemic. Efforts have focused on the development of new, less toxic and more efficacious antifungal drugs with novel mechanism of action. The purpose of this study was to synthesize of some new benzimidazole, benzotriazole and aminothiazole derivatives and to evaluate their activity...